On the chairman assignment problem

AbstractGiven m states, which form a union, every year a chairman has to be selected in such a way that at any time the accumulated number of chairmen from each state is proportional to its weight. In this paper an algorithm for a chairman assignment is given which, depending on the weights, guarantees a small discrepancy

Conditional vorticity budget of coherent and incoherent flow contributions in fully developed homogeneous isotropic turbulence

We investigate the conditional vorticity budget of fully developed three-dimensional homogeneous isotropic turbulence with respect to coherent and incoherent flow contributions. The Coherent Vorticity Extraction based on orthogonal wavelets allows to decompose the vorticity field into coherent and incoherent contributions, of which the latter are noise-like. The impact of the vortex structures observed in fully developed turbulence on statistical balance equations is quantified considering the conditional vorticity budget. The connection between the basic structures present in the flow and their statistical implications is thereby assessed. The results are compared to those obtained for large- and small-scale contributions using a Fourier decomposition, which reveals pronounced differences

Analysing Errors of Open Information Extraction Systems

We report results on benchmarking Open Information Extraction (OIE) systems using RelVis, a toolkit for benchmarking Open Information Extraction systems. Our comprehensive benchmark contains three data sets from the news domain and one data set from Wikipedia with overall 4522 labeled sentences and 11243 binary or n-ary OIE relations. In our analysis on these data sets we compared the performance of four popular OIE systems, ClausIE, OpenIE 4.2, Stanford OpenIE and PredPatt. In addition, we evaluated the impact of five common error classes on a subset of 749 n-ary tuples. From our deep analysis we unreveal important research directions for a next generation of OIE systems.Comment: Accepted at Building Linguistically Generalizable NLP Systems at EMNLP 201

Optimization and Evaluation of a Hapten Microarray Using Chemometric Methods

AbstractThe demands for the assessment of water quality are increasing steadily, making it necessary to routinely monitor multiple contaminants in water samples. For this application a hapten microarray was developed. In order to reach the required low detection limits a design of experiments (DoE) approach was used to optimize the assay performance. Here we show that a Box-Behnken design plan is an adequate choice for the straightforward exploration of hapten microarray assay parameters. For both read-out systems studied (fluorophore-labelled detection antibodies or enzymatic signal development followed by reflectometric scan, respectively), it was possible to significantly extend the measurement ranges. Furthermore, it could be shown that multivariate data analysis, here partial least squares regression (PLS), can improve the prediction accuracy of “unknown” samples when used as calibration model, compared to classical, univariate data evaluation methods

Development of a Lateral Flow Immunoassay (LFIA) to Screen for the Release of the Endocrine Disruptor Bisphenol A from Polymer Materials and Products

One of the most important chemicals used in the production of polymer plastics and coatings is bisphenol A. However, despite the large number of studies on the toxicity and hormonal activity of BPA, there are still open questions and thus considerable media attention regarding BPA toxicity. Hence, it is necessary to develop a sensitive, simple, cost-efficient, specific, portable, and rapid method for monitoring bisphenol A and for high sample throughput and on-site screening analysis. Lateral flow immunoassays have potential as rapid tests for on-site screening. To meet sensitivity criteria, they must be carefully optimized. A latex microparticle-based LFIA for detection of BPA was developed. The sensitivity of the assay was improved by non-contact printing of spot grids as the control and test lines with careful parameter optimization. Results of the test could be visually evaluated within 10 min with a visual cut-off of 10 µg/L (vLOD). Alternatively, photographs were taken, and image analysis performed to set up a calibration, which allowed for a calculated limit of detection (cLOD) of 0.14 µg/L. The method was validated for thermal paper samples against ELISA and LC–MS/MS as reference methods, showing good agreement with both methods.Bundesanstalt für Materialforschung und -PrüfungPeer Reviewe

Long-term results and complications following uvulopalatopharyngoplasty in 116 consecutive patients

A modified uvulopalatopharyngoplasty (UPPP) was carried out between January 1992 and December 2003 at the ENT Department of the Inselspital in Bern in 146 patients with habitual or complicated rhonchopathy. The operation consisted of a classical tonsillectomy or residual tonsil resection and additional shortening of the uvula. The natural mucosal fold between the uvula and the upper pole of the tonsils was carefully preserved. A wide opening to the rhinopharynx was created by asymmetric suturing of the glossopalantine and pharyngopalatine arches. A retrospective questionnaire with regard to rhonchopathy, phases of apnea, daytime drowsiness, obstruction of nasal breathing, long-term complications and patient satisfaction was used to evaluate the short-term and long-term effectiveness of the modified UPPP as well as the incidence of adverse side effects. Complete postoperative courses were evaluated in 116 patients. Surgical complications were restricted to one case with postoperative hemorrhage. A velum insufficiency or postoperative rhinopharyngeal stenosis did not occur. Eighty-three patients (72%) confirmed a persistent suppression or substantial improvement of the rhonchopathy. Disappearance or decrease of sleep apnea was confirmed in 12 (63%) out of 19 postoperative polysomnographic follow-up investigations. Long-term complications occurred in a total of 27 (23%) of 116 patients. They were confined to minor problems such as dryness of the mouth (n=12), slight difficulty in swallowing (n=7), discrete speech disturbances (n=1), and slight pharyngeal dysesthesias (n=7) with feeling of a lump in the throat and compulsive clearing of the throat. Eighty-five patients (73%) reported that they were satisfied with the postoperative result even several years after the operation. Looking back, 31 patients (27%) would no longer have the operation performed. The inadequate result of the rhonchopathy was specified as the reason by 21 patients. Ten patients had unpleasant memories of the operation because of intensive postoperative pain. Snoring and apneic phases are suppressed or improved by non-traumatic UPPP in the majority of patients. This effect persisted even years after the operatio

Machine Support of Relational Computations: The Kiel RELVIEW System

People working with relations and graphs very often use a greater or smaller example and manipulate it with pencil and paper in order to prove or disprove some property or to obtain an impression how a certain algorithm works. For supporting such a task by machine, the RELVIEW system has been constructed. This report is intended as a user's and programmer's guide for RELVIEW. But it informs also about relational algebra, the theoretical background behind the system